4. Preoperative assessment and management of bleeding diathesis and thrombosis

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Perioperative evaluation of bleeding diathesis.

The differential diagnosis of a long APTT with a normal prothrombin time can be due to either a clotting factor deficiency or the presence of an inhibitor, which can be distinguished by using a plasma-mixing study. The various clotting factor deficiency states are reviewed. Clinical bleeding following cardiac bypass surgery due to acquired factor V and thrombin antibodies is also reviewed.

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ژورنال

عنوان ژورنال: Japanese Journal of Thrombosis and Hemostasis

سال: 2007

ISSN: 1880-8808,0915-7441

DOI: 10.2491/jjsth.18.563